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CATH Superfamily 3.90.180.10

Medium-chain alcohol dehydrogenases, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Medium-chain alcohol dehydrogenases, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
S-
hydroxymethyl
1463
3D
 3qj5B01 - 93.6
2
Alcohol dehydrogenase AdhP
602
3D
 5envB01 - 95.9
3
L-threonine 3-dehydrogenase
471
3D
 3gfbD01 - 70.6
4
probable cinnamyl alcohol dehydrogenase
390
3D
 2cf6A01 - 93.4
5
Quinone oxidoreductase 1
294
3D
 3qwbD01 - 95.5
6
Alcohol dehydrogenase 1
232
3D
 4rquB01 - 78.3
7
Alcohol dehydrogenase 6
197 - - 91.9
8
Sorbitol dehydrogenase
194
3D
 1pl8D01 - 85.7
9
Reticulon-4-interacting protein 1, mitochondrial
146
3D
 2vn8B01 - 93.0
10
Enoyl-[acyl-carrier-protein] reductase, mitochondrial
144
3D
 2vcyB01 - 81.1
12
Quinone oxidoreductase yhdH
120
3D
 1o8cD01 - 43.3
11
Crotonyl-CoA carboxylase/reductase
117 - - 43.4
13
L-arabinitol 4-dehydrogenase
102
3D
 3m6iB01 - 44.9
14
Cinnamyl alcohol dehydrogenase 2
91 - - 88.0
15
Fatty acid synthase
90
3D
 2vz9B07 - 74.3
19
Prostaglandin reductase 2
85
3D
 2y05D01 - 82.4
17
NADP-dependent alcohol dehydrogenase
78
3D
 1q1nA01 - 79.0
16
Quinone oxidoreductase
77
3D
 1yb5B01 - 93.4
18
NAD
P
70 - - 88.5
20
Crotonyl-CoA reductase
62 - - 39.3
21
Galactitol-1-phosphate 5-dehydrogenase
59
3D
 4ueoB01 - 10.7
23
Prostaglandin reductase 3 isoform 1
57
3D
 2x7hB01 - 77.1
22
NADP-dependent alcohol dehydrogenase
49 - - 96.3
24
Glutathione-independent formaldehyde dehydrogenase
45 - - 22.0
25
Zinc-type alcohol dehydrogenase YahK
43
3D
 1uufA01 - 34.8
49
NADPH-dependent oxidoreductase 2-alkenal reductase
41
3D
 2j3kB01 - 83.2
26
Chlorophyll synthesis pathway protein BchC
39 - - 14.1
28
Probable polyketide synthase 16
36
3D
 5dp2A01 - 88.2
27
Zinc-type alcohol dehydrogenase AdhD
36 - - 51.4
33
Quinone oxidoreductase PIG3
35
3D
 2obyE01 - 77.7
29
Mitochondrial enoyl reductase
33 - - 65.8
32
Probable polyketide synthase pks1
32
3D
 3slkB02 - 76.3
74
Glucose 1-dehydrogenase
31
3D
 2cdcD01 - 83.2
31
R,R
30 - - 65.3
30
Synaptic vesicle membrane protein VAT-1 homolog
30 - - 46.3
47
R
29
3D
 4c4oD01 - 88.2
73
Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial
28
3D
 5lbxB01 - 35.0
35
Multifunctional mycocerosic acid synthase
27 - - 74.8
34
L-idonate 5-dehydrogenase
27 - - 1.4
36
Zinc-dependent alcohol dehydrogenase
25 - - 26.9
39
Ast1p
23 - - 35.8
37
Conserved protein
23 - - 26.1
38
Ast1p
23 - - 83.2
40
Nuclear receptor binding factor-like protein
19 - - 87.3
41
Uncharacterized protein, isoform B
18 - - 75.3
42
Erythritol/L-threitol dehydrogenase
17 - - 23.8
43
Alcohol dehydrogenase, variant
14 - - 93.1
44
Glutathione-dependent formaldehyde dehydrogenase
14 - - 17.9
45
NADP-dependent alcohol dehydrogenase
14 - - 7.7
46
2-enoyl thioester reductase
14 - - 70.4
75
Glucose 1-dehydrogenase
13
3D
 2vwqA01 - 22.1
48
Protein YIM1
13 - - 2.5
50
Unplaced genomic scaffold supercont2.5, whole genome shotgun sequence
12 - - 37.0
51
Alcohol dehydrogenase
Zinc
11 - - 64.4
55
GroES-like protein
11 - - 14.5
52
Alcohol dehydrogenase, zinc-containing
11 - - 75.5
53
Chloroplast envelope quinone oxidoreductase homolog
11 - - 16.8
54
Probable NADPH quinone oxidoreductase fadB4
11 - - 0.0
56
NAD-dependent alcohol dehydrogenase
11 - - 11.0
60
Crystallin zeta like 1
10 - - 16.9
57
Putative alcohol dehydrogenase
10 - - 34.1
59
YML131W-like protein
10 - - 0.0
58
Alcohol dehydrogenase 2
10 - - 14.1
61
Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence
10 - - 56.5
68
Phthioceranic/hydroxyphthioceranic acid synthase
9 - - 0.4
66
Putative quinone oxidoreductase
9 - - 5.7
67
alcohol dehydrogenase 1-like isoform X1
9 - - 89.4
69
Putative NADP-dependent alcohol dehydrogenase
9 - - 100.0
64
NADPH-dependent alkenal/one oxidoreductase, chloroplastic
9 - - 15.6
62
Related to ADH2-Alcohol dehydrogenase II
9 - - 21.1
63
Probable alcohol dehydrogenase adhA
9 - - 4.4
65
Zinc-binding dehydrogenase family protein
9 - - 10.7
72
Crystallin zeta
8 - - 96.8
70
Mitochondrial enoyl reductase, putative
8 - - 27.4
71
NAD-dependent alcohol dehydrogenase
8 - - 88.8
77
Alcohol dehydrogenase
7 - - 10.9
76
Unplaced genomic scaffold supercont1.219, whole genome shotgun sequence
7 - - 15.1
81
Unplaced genomic scaffold supercont1.1, whole genome shotgun sequence
6 - - 10.6
82
Reticulon-4-interacting protein 1, mitochondrial
6 - - 87.0
80
Alcohol dehydrogenase, zinc-binding
6 - - 20.6
78
Quinone oxidoreductase
6 - - 67.8
79
Quinone oxidoreductase
6 - - 14.5
91
Aspergillus niger contig An11c0010, genomic contig
5 - - 5.7
85
Alcohol dehydrogenase
5 - - 7.2
83
Zinc-binding dehydrogenase-like protein
5 - - 67.5
90
Possible dehydrogenase
5 - - 0.0
84
NADH oxidoreductase
5 - - 18.5
92
Protein CBG23238
5 - - 84.2
93
Alcohol dehydrogenase 5
class III
5 - - 63.8
89
GroES-like zinc-binding alcohol dehydrogenase family protein
5 - - 17.1
87
Alcohol dehydrogenase
5 - - 0.7
86
NADP-dependent alcohol dehydrogenase
5 - - 14.2
88
Probable quinone oxidoreductase
5 - - 0.7
95
Chlorophyll synthesis pathway protein BchC
4 - - 14.4
100
Putative cinnamyl alcohol dehydrogenase 6
4 - - 74.5
94
Enoyl-[acyl-carrier-protein] reductase, mitochondrial
4 - - 63.4
99
Uncharacterized protein
4 - - 78.0
96
Quinone oxidoreductase
4 - - 0.0
97
Alcohol dehydrogenase GroES domain protein
4 - - 0.0
98
Uncharacterized protein
4 - - 10.4
102
Uncharacterized protein
3 - - 42.8
105
6-hydroxycylohex-1-en-1-carbonyl-CoA dehydrogenase
3 - - 2.3
107
Alcohol dehydrogenase
3 - - 9.9
110
Alcohol dehydrogenase
Zn containing Adh-13
3 - - 0.0
103
IMP dehydrogenase
3 - - 3.6
112
Uncharacterized protein
3 - - 61.9
108
Zinc-binding oxidoreductase, putative
3 - - 5.1
109
Acryloyl-coenzyme A reductase
3 - - 17.4
111
Putative NADP-dependent alcohol dehydrogenase
3 - - 74.2
104
Zinc-binding dehydrogenase family oxidoreductase
3 - - 0.0
101
Alcohol dehydrogenase 6B
class V
3 - - 64.3
106
Quinone oxidoreductase
3 - - 2.1
118
Uncharacterized protein
2 - - 3.3
119
Protein CBG06201
2 - - 2.9
120
Quinone oxidoreductase-like protein 2
2 - - 7.0
130
Uncharacterized protein
2 - - 0.0
132
Uncharacterized protein
2 - - 0.0
117
Uncharacterized protein
2 - - 0.0
122
Lovastatin nonaketide synthase, enoyl reductase component
2 - - 1.5
113
Geraniol dehydrogenase GeoA
2 - - 0.0
135
Uncharacterized protein
2 - - 40.8
125
Putative mannitol dehydrogenase
2 - - 0.0
140
Uncharacterized protein
2 - - 29.0
139
Quinone oxidoreductase, putative
2 - - 40.1
138
Uncharacterized protein
2 - - 37.7
129
Alcohol dehydrogenase 5
class III
2 - - 35.5
128
Uncharacterized protein
2 - - 1.6
127
Alcohol dehydrogenase-like 6
2 - - 4.0
137
Lovastatin diketide synthase LovF
2 - - 3.2
115
Uncharacterized protein
2 - - 0.0
133
Uncharacterized protein
2 - - 0.0
123
Enoyl-[acyl-carrier-protein] reductase, mitochondrial
2 - - 0.0
116
Alcohol dehydrogenase, zinc-containing
2 - - 12.2
134
Uncharacterized protein
2 - - 42.0
124
Uncharacterized protein
2 - - 5.4
141
Uncharacterized protein
2 - - 20.3
114
Uncharacterized protein
2 - - 0.7
136
Alcohol dehydrogenase, putative
AFU_orthologue AFUA_2G04590
2 - - 0.0
126
Uncharacterized protein
2 - - 36.9
131
Uncharacterized protein
2 - - 0.0
121
Predicted protein
2 - - 0.0
153
Putative oxidoreductase
1 - - 0.0
184
Uncharacterized protein
1 - - 0.0
191
Uncharacterized protein
1 - - 0.0
142
Uncharacterized protein
1 - - 0.0
161
Uncharacterized protein
1 - - 0.0
157
Os11g0210600 protein
1 - - 0.0
145
Uncharacterized protein
1 - - 0.0
171
Uncharacterized protein
1 - - 0.0
166
Uncharacterized protein
1 - - 0.0
176
Uncharacterized protein
1 - - 0.0
158
Dehydrogenase orsE
1 - - 0.0
159
Predicted protein
1 - - 0.0
196
Uncharacterized protein
1 - - 0.0
147
2-haloacrylate reductase
1 - - 0.0
155
Zinc-type alcohol dehydrogenase-like protein C16A3.02c
1 - - 0.0
186
Putative cinnamyl alcohol dehydrogenase 6
1 - - 0.0
201
Uncharacterized protein
1 - - 0.0
152
Uncharacterized protein
1 - - 0.0
143
Zinc-type alcohol dehydrogenase-like protein C1198.01
1 - - 0.0
150
Predicted protein
1 - - 0.0
164
Uncharacterized protein
1 - - 0.0
148
S or R-dihydroxypropanesulfonate-2-dehydrogenase
1 - - 0.0
149
Uncharacterized protein
1 - - 0.0
174
Uncharacterized protein
1 - - 0.0
181
Zinc-type alcohol dehydrogenase-like protein C337.11
1 - - 0.0
194
Uncharacterized protein
1 - - 0.0
180
Uncharacterized protein
1 - - 0.0
163
Zinc-type alcohol dehydrogenase-like protein C2E1P3.01
1 - - 0.0
197
Uncharacterized protein
1 - - 0.0
202
Uncharacterized protein
1 - - 0.0
173
Uncharacterized protein
1 - - 0.0
177
Uncharacterized protein
1 - - 0.0
151
D-arabinitol dehydrogenase 1
1 - - 0.0
193
Uncharacterized protein
1 - - 0.0
167
Uncharacterized protein
1 - - 0.0
156
Uncharacterized protein
1 - - 0.0
185
Alcohol dehydrogenase-like 3
1 - - 0.0
198
Uncharacterized protein
1 - - 0.0
199
Uncharacterized protein
1 - - 0.0
169
Uncharacterized protein
1 - - 0.0
168
Predicted protein
1 - - 0.0
182
Uncharacterized protein
1 - - 0.0
144
Uncharacterized protein
1 - - 0.0
179
Predicted protein
1 - - 0.0
178
Sorbitol dehydrogenase
1 - - 0.0
200
Asperfuranone polyketide synthase afoG
1 - - 0.0
165
Uncharacterized protein
1 - - 0.0
192
Uncharacterized protein
1 - - 0.0
175
Uncharacterized protein
1 - - 0.0
162
Uncharacterized protein
1 - - 0.0
188
Uncharacterized protein
1 - - 0.0
189
Uncharacterized protein
1 - - 0.0
195
Uncharacterized protein
1 - - 0.0
172
Uncharacterized protein
1 - - 0.0
183
Protein CBG23238
1 - - 0.0
160
Uncharacterized protein
1 - - 0.0
154
Predicted protein
1 - - 0.0
170
Uncharacterized protein
1 - - 0.0
187
Uncharacterized protein
1 - - 0.0
146
L-idonate 5-dehydrogenase
1 - - 0.0
190
Alcohol dehydrogenase-like 3
1 - - 0.0
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