CATH Domain 6dekA03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.970	Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains

Domain Context

CATH Clusters

Superfamily	3.40.50.970
Functional Family	Acetolactate synthase, mitochondrial

Enzyme Information

UniProtKB Entries (1)

A0A1D8PJF9_CANAL

Candida albicans SC5314

Acetolactate synthase

PDB Structure

PDB	6DEK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Garcia, M.D., Chua, S.M.H., Low, Y.S., Lee, Y.T., Agnew-Francis, K., Wang, J.G., Nouwens, A., Lonhienne, T., Williams, C.M., Fraser, J.A., Guddat, L.W. Proc. Natl. Acad. Sci. U.S.A.