CATH Classification

Domain Context

CATH Clusters

Superfamily Substrate Binding Domain Of DNAk; Chain A, domain 1
Functional Family Heat shock 70 kDa

Enzyme Information

UniProtKB Entries (1)

P0DMV9
HS71B_HUMAN
Homo sapiens
Heat shock 70 kDa protein 1B

PDB Structure

PDB 4WV5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The novolactone natural product disrupts the allosteric regulation of hsp70.
Hassan, A.Q., Kirby, C.A., Zhou, W., Schuhmann, T., Kityk, R., Kipp, D.R., Baird, J., Chen, J., Chen, Y., Chung, F., Hoepfner, D., Movva, N.R., Pagliarini, R., Petersen, F., Quinn, C., Quinn, D., Riedl, R., Schmitt, E.K., Schitter, A., Stams, T., Studer, C., Fortin, P.D., Mayer, M.P., Sadlish, H.
Chem.Biol.