CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.950 | Filoviridae VP35, C-terminal inhibitory domain, helical subdomain |
Domain Context
CATH Clusters
| Superfamily | Filoviridae VP35, C-terminal inhibitory domain, helical subdomain |
| Functional Family | Polymerase cofactor VP35 |
Enzyme Information
UniProtKB Entries (1)
| Q05127 |
VP35_EBOZM
Ebola virus - Mayinga, Zaire, 1976
Polymerase cofactor VP35
|
PDB Structure
| PDB | 4IBI |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
J.Mol.Biol.
|