CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.10 | Ribbon | |
2.10.10 | Seminal Fluid Protein PDC-109 (Domain B) | |
2.10.10.70 | Filoviridae VP35, C-terminal inhibitory domain, beta-sheet subdomain |
Domain Context
CATH Clusters
Superfamily | Filoviridae VP35, C-terminal inhibitory domain, beta-sheet subdomain |
Functional Family | Polymerase cofactor VP35 |
Enzyme Information
UniProtKB Entries (1)
Q05127 |
VP35_EBOZM
Ebola virus - Mayinga, Zaire, 1976
Polymerase cofactor VP35
|
PDB Structure
PDB | 4IBG |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
J.Mol.Biol.
|