CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.10 | Ribbon |
|
2.10.10 | Seminal Fluid Protein PDC-109 (Domain B) |
|
2.10.10.70 | Filoviridae VP35, C-terminal inhibitory domain, beta-sheet subdomain |
Domain Context
CATH Clusters
| Superfamily | Filoviridae VP35, C-terminal inhibitory domain, beta-sheet subdomain |
| Functional Family | Polymerase cofactor VP35 |
Enzyme Information
UniProtKB Entries (1)
| Q05127 |
VP35_EBOZM
Ebola virus - Mayinga, Zaire, 1976
Polymerase cofactor VP35
|
PDB Structure
| PDB | 4IBB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
J.Mol.Biol.
|