CATH Domain 4gh9A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.8	Helicase, Ruva Protein; domain 3
	1.10.8.950	Filoviridae VP35, C-terminal inhibitory domain, helical subdomain

Domain Context

CATH Clusters

Superfamily	Filoviridae VP35, C-terminal inhibitory domain, helical subdomain
Functional Family	Polymerase cofactor VP35

Enzyme Information

UniProtKB Entries (1)

VP35_MABVM

Marburg virus - Musoke, Kenya, 1980

Polymerase cofactor VP35

PDB Structure

PDB	4GH9
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. Bale, S., Julien, J.P., Bornholdt, Z.A., Kimberlin, C.R., Halfmann, P., Zandonatti, M.A., Kunert, J., Kroon, G.J., Kawaoka, Y., Macrae, I.J., Wilson, I.A., Saphire, E.O. Plos Pathog.