CATH Domain 4fdcB03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.390	Enolase-like; domain 1
	3.30.390.30	FAD/NAD-linked reductase, C-terminal dimerisation domain

Domain Context

CATH Clusters

Superfamily	3.30.390.30
Functional Family	Putative apoptosis-inducing factor 1, mitochondrial

Enzyme Information

1.1.1.-

With NAD(+) or NADP(+) as acceptor.

based on mapping to UniProt O95831

UniProtKB Entries (1)

AIFM1_HUMAN

Homo sapiens

Apoptosis-inducing factor 1, mitochondrial

PDB Structure

PDB	4FDC
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Cowchock syndrome is associated with a mutation in apoptosis-inducing factor. Rinaldi, C., Grunseich, C., Sevrioukova, I.F., Schindler, A., Horkayne-Szakaly, I., Lamperti, C., Landoure, G., Kennerson, M.L., Burnett, B.G., Bonnemann, C., Biesecker, L.G., Ghezzi, D., Zeviani, M., Fischbeck, K.H. Am.J.Hum.Genet.