CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.21 | Purple Acid Phosphatase; chain A, domain 2 |
|
3.60.21.10 | Metallo-dependent phosphatases |
Domain Context
CATH Clusters
| Superfamily | 3.60.21.10 |
| Functional Family | Fe(3+)-Zn(2+) purple acid phosphatase |
Enzyme Information
| 3.1.3.2 |
Acid phosphatase.
based on mapping to UniProt P80366
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Wide specificity. -!- Also catalyzes transphosphorylations.
|
UniProtKB Entries (1)
| P80366 |
PPAF_PHAVU
Phaseolus vulgaris
Fe(3+)-Zn(2+) purple acid phosphatase
|
PDB Structure
| PDB | 4DHL |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des.
|
