CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.130 | Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain |
Domain Context
CATH Clusters
| Superfamily | 1.10.287.130 |
| Functional Family | Sensor histidine kinase CpxA |
Enzyme Information
| 2.7.13.3 |
Histidine kinase.
based on mapping to UniProt P0AE82
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
|
UniProtKB Entries (1)
| P0AE82 |
CPXA_ECOLI
Escherichia coli K-12
Sensor histidine kinase CpxA
|
PDB Structure
| PDB | 4BIU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
Plos Biol.
|
