CATH Classification

Domain Context

CATH Clusters

Superfamily Filoviridae VP35, C-terminal inhibitory domain, beta-sheet subdomain
Functional Family Polymerase cofactor VP35

Enzyme Information

UniProtKB Entries (1)

Q8JPY0
VP35_EBORR
Reston ebolavirus - Reston (1989)
Polymerase cofactor VP35

PDB Structure

PDB 3KS4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression.
Kimberlin, C.R., Bornholdt, Z.A., Li, S., Woods, V.L., Macrae, I.J., Saphire, E.O.
Proc.Natl.Acad.Sci.USA
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