CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.950 | Filoviridae VP35, C-terminal inhibitory domain, helical subdomain |
Domain Context
CATH Clusters
| Superfamily | Filoviridae VP35, C-terminal inhibitory domain, helical subdomain |
| Functional Family | Polymerase cofactor VP35 |
Enzyme Information
UniProtKB Entries (1)
| Q8JPY0 |
VP35_EBORR
Reston ebolavirus - Reston (1989)
Polymerase cofactor VP35
|
PDB Structure
| PDB | 3KS4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression.
Proc.Natl.Acad.Sci.USA
|
