CATH Domain 3k66A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.120	Four Helix Bundle (Hemerythrin (Met), subunit A)
	1.20.120.770	Amyloid precursor protein, E2 domain

Domain Context

CATH Clusters

Superfamily	Amyloid precursor protein, E2 domain
Functional Family	Amyloid-beta-like protein

Enzyme Information

UniProtKB Entries (1)

A4_CAEEL

Caenorhabditis elegans

Amyloid-beta-like protein

PDB Structure

PDB	3K66
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site Hoopes, J.T., Liu, X., Xu, X., Demeler, B., Folta-Stogniew, E., Li, C., Ha, Y. J.Biol.Chem.