CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.390 | Enolase-like; domain 1 |
|
3.30.390.30 | FAD/NAD-linked reductase, C-terminal dimerisation domain |
Domain Context
CATH Clusters
| Superfamily | 3.30.390.30 |
| Functional Family | Trypanothione reductase |
Enzyme Information
UniProtKB Entries (1)
| A4HSF7 |
A4HSF7_LEIIN
Leishmania infantum
Trypanothione reductase
|
PDB Structure
| PDB | 2YAU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
A Gold-Containing Drug Against Parasitic Polyamine Metabolism: The X-Ray Structure of Trypanothione Reductase from Leishmania Infantum in Complex with Auranofin Reveals a Dual Mechanism of Enzyme Inhibition.
Amino Acids
|
