CATH Domain 2rg1A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.360	Flavodoxin domain

Domain Context

CATH Clusters

Superfamily	3.40.50.360
Functional Family	NAD(P)H dehydrogenase (quinone)

Enzyme Information

1.6.5.2

NAD(P)H dehydrogenase (quinone).

based on mapping to UniProt P0A8G6

NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone.

-!- The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone. -!- The animal, but not the plant, form of the enzyme is inhibited by dicoumarol. -!- Formerly EC 1.6.99.2.

UniProtKB Entries (1)

P0A8G6

NQOR_ECOLI

Escherichia coli K-12

NAD(P)H dehydrogenase (quinone)

PDB Structure

PDB	2RG1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural organization of WrbA in apo- and holoprotein crystals. Wolfova, J., Smatanova, I.K., Brynda, J., Mesters, J.R., Lapkouski, M., Kuty, M., Natalello, A., Chatterjee, N., Chern, S.Y., Ebbel, E., Ricci, A., Grandori, R., Ettrich, R., Carey, J. Biochim.Biophys.Acta