CATH Domain 2cogA01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.470	D-amino Acid Aminotransferase; Chain A, domain 1
	3.30.470.10	Aminotransferase class 4, branched-chain amino acid transferase, N-terminal domain

Superfamily	3.30.470.10
Functional Family	Branched-chain-amino-acid aminotransferase

2.6.1.42

Branched-chain-amino-acid transaminase.

based on mapping to UniProt P54687

L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.

-!- Also acts on L-isoleucine and L-valine. -!- Different from EC 2.6.1.66.

BCAT1_HUMAN

Homo sapiens

Branched-chain-amino-acid aminotransferase, cytosolic

PDB	2COG
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin Goto, M., Miyahara, I., Hirotsu, K., Conway, M., Yennawar, N., Islam, M.M., Hutson, S.M. J.Biol.Chem.