CATH Classification
Domain Context
CATH Clusters
Superfamily | 3-hydroxy-3-methylglutaryl-coenzyme A Reductase; Chain A, domain 2 |
Functional Family |
Enzyme Information
1.1.1.88 |
Hydroxymethylglutaryl-CoA reductase.
based on mapping to UniProt P13702
(R)-mevalonate + CoA + 2 NAD(+) = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.
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UniProtKB Entries (1)
P13702 |
MVAA_PSEMV
Pseudomonas mevalonii
3-hydroxy-3-methylglutaryl-coenzyme A reductase
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PDB Structure
PDB | 1T02 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | Escherichia |
Primary Citation |
Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase.
J.Biol.Chem.
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