CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.90 | Phospholipase A2 | |
1.20.90.10 | Phospholipase A2 domain |
Domain Context
CATH Clusters
Superfamily | Phospholipase A2 domain |
Functional Family | Phospholipase A2 group III |
Enzyme Information
3.1.1.4 |
Phospholipase A(2).
based on mapping to UniProt P00630
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.
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UniProtKB Entries (1)
P00630 |
PA2_APIME
Apis mellifera
Phospholipase A2
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PDB Structure
PDB | 1POC |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.
Science
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