CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.20 | Up-down Bundle | |
1.20.1280 | Monooxygenase | |
1.20.1280.10 | Methane monooxygenase, gamma chain, domain 1 |
Domain Context
CATH Clusters
Superfamily | Methane monooxygenase, gamma chain, domain 1 |
Functional Family |
Enzyme Information
1.14.13.25 |
Methane monooxygenase (soluble).
based on mapping to UniProt P27355
Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O.
-!- The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3. -!- Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO(2), ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.
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UniProtKB Entries (1)
P27355 |
MEMG_METTR
Methylosinus trichosporium
Methane monooxygenase component A gamma chain
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PDB Structure
PDB | 1MHZ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b
Protein Sci.
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