CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2300
Functional Family Low molecular weight phosphotyrosine protein

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P11064
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
3.1.3.2
Acid phosphatase.
based on mapping to UniProt P11064
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Wide specificity. -!- Also catalyzes transphosphorylations.

UniProtKB Entries (1)

P11064
PPAC_BOVIN
Bos taurus
Low molecular weight phosphotyrosine protein phosphatase

PDB Structure

PDB 1BVH
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of a low molecular weight protein tyrosine phosphatase.
Logan, T.M., Zhou, M.M., Nettesheim, D.G., Meadows, R.P., Van Etten, R.L., Fesik, S.W.
Biochemistry
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