PDB Information

PDB6Q6K
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish.
Artola, M., Kuo, C.L., Lelieveld, L.T., Rowland, R.J., van der Marel, G.A., Codee, J.D.C., Boot, R.G., Davies, G.J., Aerts, J.M.F.G., Overkleeft, H.S.
J.Am.Chem.Soc.
HeaderHydrolase
Released2018-12-11
Resolution1.920
CATH Insert Date31 Mar, 2019

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 31 Mar, 2019 Chopped
B 31 Mar, 2019 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6q6kA01 01 Apr, 2019 3.20.20.80 Assigned
6q6kA02 01 Apr, 2019 2.60.40.1180 Assigned
6q6kB01 01 Apr, 2019 3.20.20.80 Assigned
6q6kB02 01 Apr, 2019 2.60.40.1180 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04062 GLCM_HUMAN Homo sapiens Lysosomal acid glucosylceramidase
P04062 GLCM_HUMAN Homo sapiens Lysosomal acid glucosylceramidase