PDB 6b3s

PDB Information

PDB6B3S
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Molecular Basis for Necitumumab Inhibition of EGFR Variants Associated with Acquired Cetuximab Resistance.
Bagchi, A., Haidar, J.N., Eastman, S.W., Vieth, M., Topper, M., Iacolina, M.D., Walker, J.M., Forest, A., Shen, Y., Novosiadly, R.D., Ferguson, K.M.
Mol. Cancer Ther.
HeaderTransferase/Immune System
Released2017-09-23
Resolution2.800
CATH Insert Date17 Dec, 2017

PDB Images (33)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped
B 17 Dec, 2017 Chopped
C 17 Dec, 2017 Chopped
D 17 Dec, 2017 Chopped
E 17 Dec, 2017 Chopped
F 17 Dec, 2017 Chopped
G 17 Dec, 2017 Chopped
H 17 Dec, 2017 Chopped
I 17 Dec, 2017 Chopped
J 17 Dec, 2017 Chopped
K 17 Dec, 2017 Chopped
L 17 Dec, 2017 Chopped

CATH Domains (20)

Domain ID Date inserted into CATH Superfamily CATH Status
6b3sA00 23 Dec, 2017 3.80.20.20 Assigned
6b3sB00 23 Dec, 2017 3.80.20.20 Assigned
6b3sC01 23 Dec, 2017 Holding pen
6b3sC02 23 Dec, 2017 2.60.40.10 Assigned
6b3sD01 12 Jul, 2018 2.60.40.10 Assigned
6b3sD02 12 Jul, 2018 2.60.40.10 Assigned
6b3sE00 23 Dec, 2017 3.80.20.20 Assigned
6b3sF01 23 Dec, 2017 Holding pen
6b3sF02 23 Dec, 2017 2.60.40.10 Assigned
6b3sG01 12 Jul, 2018 2.60.40.10 Assigned
6b3sG02 12 Jul, 2018 2.60.40.10 Assigned
6b3sH01 23 Dec, 2017 Holding pen
6b3sH02 23 Dec, 2017 2.60.40.10 Assigned
6b3sI00 23 Dec, 2017 3.80.20.20 Assigned
6b3sJ01 23 Dec, 2017 Holding pen
6b3sJ02 23 Dec, 2017 2.60.40.10 Assigned
6b3sK01 12 Jul, 2018 2.60.40.10 Assigned
6b3sK02 12 Jul, 2018 2.60.40.10 Assigned
6b3sL01 12 Jul, 2018 2.60.40.10 Assigned
6b3sL02 12 Jul, 2018 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor