PDB 6b2q

PDB Information

PDB6B2Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.
Wang, T., Bemis, G., Hanzelka, B., Zuccola, H., Wynn, M., Moody, C.S., Green, J., Locher, C., Liu, A., Gao, H., Xu, Y., Wang, S., Wang, J., Bennani, Y.L., Thomson, J.A., Muh, U.
ACS Med Chem Lett
HeaderTransferase/Inhibitor
Released2017-09-20
Resolution2.880
CATH Insert Date03 Jun, 2018

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped
C 03 Jun, 2018 Chopped
D 03 Jun, 2018 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
6b2qA01 28 Jun, 2018 3.30.200.20 Assigned
6b2qA02 28 Jun, 2018 1.10.510.10 Assigned
6b2qB01 28 Jun, 2018 3.30.200.20 Assigned
6b2qB02 28 Jun, 2018 1.10.510.10 Assigned
6b2qC01 28 Jun, 2018 3.30.200.20 Assigned
6b2qC02 28 Jun, 2018 1.10.510.10 Assigned
6b2qD01 28 Jun, 2018 3.30.200.20 Assigned
6b2qD02 28 Jun, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P9WI83 PKNA_MYCTU Mycobacterium tuberculosis H37Rv Serine/threonine-protein kinase PknA
P9WI83 PKNA_MYCTU Mycobacterium tuberculosis H37Rv Serine/threonine-protein kinase PknA
P9WI83 PKNA_MYCTU Mycobacterium tuberculosis H37Rv Serine/threonine-protein kinase PknA
P9WI83 PKNA_MYCTU Mycobacterium tuberculosis H37Rv Serine/threonine-protein kinase PknA