PDB Information

PDB5UX4
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceRattus norvegicus
Primary Citation
Development of 2-aminooxazoline 3-azaxanthene beta-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D.
Low, J.D., Bartberger, M.D., Chen, K., Cheng, Y., Fielden, M.R., Gore, V., Hickman, D., Liu, Q., Allen Sickmier, E., Vargas, H.M., Werner, J., White, R.D., Whittington, D.A., Wood, S., Minatti, A.E.
Medchemcomm
HeaderHydrolase
Released2017-02-22
Resolution2.810
CATH Insert Date06 Jul, 2018

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Jul, 2018 Chopped
B 06 Jul, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5ux4A01 19 Jul, 2018 2.40.70.10 Assigned
5ux4A02 19 Jul, 2018 2.40.70.10 Assigned
5ux4B01 19 Jul, 2018 2.40.70.10 Assigned
5ux4B02 19 Jul, 2018 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P24268 CATD_RAT Rattus norvegicus Cathepsin D
P24268 CATD_RAT Rattus norvegicus Cathepsin D