PDB Information

PDB5U6X
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceOvis aries
Primary Citation
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6).
Cingolani, G., Panella, A., Perrone, M.G., Vitale, P., Di Mauro, G., Fortuna, C.G., Armen, R.S., Ferorelli, S., Smith, W.L., Scilimati, A.
Eur J Med Chem
HeaderOxidoreductase
Released2016-12-09
Resolution2.930
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5u6xA01 10 Dec, 2017 2.10.25.10 Assigned
5u6xA02 10 Dec, 2017 1.10.640.10 Assigned
5u6xB01 10 Dec, 2017 2.10.25.10 Assigned
5u6xB02 10 Dec, 2017 1.10.640.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P05979 PGH1_SHEEP Ovis aries Prostaglandin G/H synthase 1
P05979 PGH1_SHEEP Ovis aries Prostaglandin G/H synthase 1