PDB Information

PDB5OBJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase-TPX2 protein-protein interaction.
Cole, D.J., Janecek, M., Stokes, J.E., Rossmann, M., Faver, J.C., McKenzie, G.J., Venkitaraman, A.R., Hyvonen, M., Spring, D.R., Huggins, D.J., Jorgensen, W.L.
Chem. Commun. (Camb.)
HeaderCell Cycle
Released2017-06-28
Resolution2.900
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5objA01 10 Dec, 2017 3.30.200.20 Assigned
5objA02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A