PDB Information

PDB5LOH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct.
Ocasio, C.A., Rajasekaran, M.B., Walker, S., Le Grand, D., Spencer, J., Pearl, F.M., Ward, S.E., Savic, V., Pearl, L.H., Hochegger, H., Oliver, A.W.
Oncotarget
HeaderTransferase
Released2016-08-09
Resolution3.100
CATH Insert Date09 Oct, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Oct, 2016 Chopped
B 10 Oct, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5lohA01 14 Oct, 2016 3.30.200.20 Assigned
5lohA02 14 Oct, 2016 1.10.510.10 Assigned
5lohB01 13 Oct, 2016 3.30.200.20 Assigned
5lohB02 13 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q96GX5 GWL_HUMAN Homo sapiens Serine/threonine-protein kinase greatwall
Q96GX5 GWL_HUMAN Homo sapiens Serine/threonine-protein kinase greatwall