PDB Information

PDB5KU9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMUS MUSCULUS, HOMO SAPIENS
Primary Citation
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
Johannes, J.W., Bates, S., Beigie, C., Belmonte, M.A., Breen, J., Cao, S., Centrella, P.A., Clark, M.A., Cuozzo, J.W., Dumelin, C.E., Ferguson, A.D., Habeshian, S., Hargreaves, D., Joubran, C., Kazmirski, S., Keefe, A.D., Lamb, M.L., Lan, H., Li, Y., Ma, H., Mlynarski, S., Packer, M.J., Rawlins, P.B., Robbins, D.W., Shen, H., Sigel, E.A., Soutter, H.H., Su, N., Troast, D.M., Wang, H., Wickson, K.F., Wu, C., Zhang, Y., Zhao, Q., Zheng, X., Hird, A.W.
ACS Med Chem Lett
HeaderHydrolase/Hydrolase Inhibitor
Released2016-07-13
Resolution2.200
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ku9A01 14 May, 2017 1.10.437.10 Assigned
5ku9B01 13 May, 2017 1.10.437.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
P97287 MCL1_MOUSE Mus musculus Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
P97287 MCL1_MOUSE Mus musculus Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
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