CATH Classification

Domain Context

CATH Clusters

Superfamily Blc2-like
Functional Family Induced myeloid leukemia cell differentiation protein Mcl-1

Enzyme Information

UniProtKB Entries (2)

P97287
MCL1_MOUSE
Mus musculus
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Q07820
MCL1_HUMAN
Homo sapiens
Induced myeloid leukemia cell differentiation protein Mcl-1

PDB Structure

PDB 5KU9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
Johannes, J.W., Bates, S., Beigie, C., Belmonte, M.A., Breen, J., Cao, S., Centrella, P.A., Clark, M.A., Cuozzo, J.W., Dumelin, C.E., Ferguson, A.D., Habeshian, S., Hargreaves, D., Joubran, C., Kazmirski, S., Keefe, A.D., Lamb, M.L., Lan, H., Li, Y., Ma, H., Mlynarski, S., Packer, M.J., Rawlins, P.B., Robbins, D.W., Shen, H., Sigel, E.A., Soutter, H.H., Su, N., Troast, D.M., Wang, H., Wickson, K.F., Wu, C., Zhang, Y., Zhao, Q., Zheng, X., Hird, A.W.
ACS Med Chem Lett
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