PDB Information

PDB5KIT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors.
Zak, M., Yuen, P.W., Liu, X., Patel, S., Sampath, D., Oeh, J., Liederer, B.M., Wang, W., O'Brien, T., Xiao, Y., Skelton, N., Hua, R., Sodhi, J., Wang, Y., Zhang, L., Zhao, G., Zheng, X., Ho, Y.C., Bair, K.W., Dragovich, P.S.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-06-17
Resolution1.600
CATH Insert Date16 Oct, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5kitA01 21 Oct, 2016 Holding pen
5kitA02 21 Oct, 2016 3.20.20.70 Assigned
5kitB01 22 Oct, 2016 Holding pen
5kitB02 22 Oct, 2016 3.20.20.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P43490 NAMPT_HUMAN Homo sapiens Nicotinamide phosphoribosyltransferase
P43490 NAMPT_HUMAN Homo sapiens Nicotinamide phosphoribosyltransferase