CATH Domain 5kitA02

Superfamily	Aldolase class I
Functional Family

2.4.2.12

Nicotinamide phosphoribosyltransferase.

based on mapping to UniProt P43490

Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho- alpha-D-ribose 1-diphosphate.

NAMPT_HUMAN

Homo sapiens

Nicotinamide phosphoribosyltransferase

PDB	5KIT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. Zak, M., Yuen, P.W., Liu, X., Patel, S., Sampath, D., Oeh, J., Liederer, B.M., Wang, W., O'Brien, T., Xiao, Y., Skelton, N., Hua, R., Sodhi, J., Wang, Y., Zhang, L., Zhao, G., Zheng, X., Ho, Y.C., Bair, K.W., Dragovich, P.S. J.Med.Chem.