PDB 5k0m

PDB Information

PDB5K0M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex.
He, Y., Selvaraju, S., Curtin, M.L., Jakob, C.G., Zhu, H., Comess, K.M., Shaw, B., The, J., Lima-Fernandes, E., Szewczyk, M.M., Cheng, D., Klinge, K.L., Li, H.Q., Pliushchev, M., Algire, M.A., Maag, D., Guo, J., Dietrich, J., Panchal, S.C., Petros, A.M., Sweis, R.F., Torrent, M., Bigelow, L.J., Senisterra, G., Li, F., Kennedy, S., Wu, Q., Osterling, D.J., Lindley, D.J., Gao, W., Galasinski, S., Barsyte-Lovejoy, D., Vedadi, M., Buchanan, F.G., Arrowsmith, C.H., Chiang, G.G., Sun, C., Pappano, W.N.
Nat. Chem. Biol.
HeaderProtein Binding
Released2016-05-17
Resolution1.830
CATH Insert Date07 May, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5k0mA00 14 Dec, 2017 2.130.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O75530 EED_HUMAN Homo sapiens Polycomb protein EED