PDB 5ism

PDB Links
Overview

PDB Information

PDB	5ISM
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors. Cox, J.M., Chu, H.D., Kuethe, J.T., Gao, Y.D., Scapin, G., Eiermann, G., He, H., Li, X., Lyons, K.A., Metzger, J., Petrov, A., Wu, J.K., Xu, S., Sinha-Roy, R., Weber, A.E., Biftu, T. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-03-15
Resolution	2.000
CATH Insert Date	29 May, 2016

PDB Images (7)

Image of CATH 5ism

5ism

PDB 5ism

Image of CATH 5ismA

5ismA

PDB Chain 5ismA

Image of CATH 5ismB

5ismB

PDB Chain 5ismB

Image of CATH 5ismA01

5ismA01

CATH Domain 5ismA01

Image of CATH 5ismA02

5ismA02

CATH Domain 5ismA02

Image of CATH 5ismB01

5ismB01

CATH Domain 5ismB01

Image of CATH 5ismB02

5ismB02

CATH Domain 5ismB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	30 May, 2016	Chopped
B	30 May, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5ismA01	18 Jul, 2016	3.40.50.1820	Assigned
5ismA02	18 Jul, 2016	2.140.10.30	Assigned
5ismB01	18 Jul, 2016	3.40.50.1820	Assigned
5ismB02	18 Jul, 2016	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4