PDB 5hs3
PDB Information
PDB | 5HS3 |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Nat Commun
|
Header | Transferase/Transferase Inhibitor |
Released | 2016-01-25 |
Resolution | 3.100 |
CATH Insert Date | 10 Apr, 2016 |
PDB Images (13)
PDB Prints
PDB Chains (6)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 11 Apr, 2016 | Chopped |
B | 11 Apr, 2016 | Chopped |
C | 11 Apr, 2016 | Chopped |
D | 11 Apr, 2016 | Chopped |
E | 11 Apr, 2016 | Chopped |
F | 11 Apr, 2016 | Chopped |
CATH Domains (6)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
5hs3A00 | 14 May, 2016 | 3.30.572.10 | Assigned |
5hs3B00 | 14 May, 2016 | 3.30.572.10 | Assigned |
5hs3C00 | 14 May, 2016 | 3.30.572.10 | Assigned |
5hs3D00 | 14 May, 2016 | 3.30.572.10 | Assigned |
5hs3E00 | 14 May, 2016 | 3.30.572.10 | Assigned |
5hs3F00 | 14 May, 2016 | 3.30.572.10 | Assigned |
UniProtKB Entries (6)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |
P04818 | TYSY_HUMAN | Homo sapiens | Thymidylate synthase |