PDB Information

PDB5FW6
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sant'Anna, R., Almeida, M.R., Varejao, N., Gallego, P., Esperante, S., Ferreira, P., Pereira-Henriques, A., Palhano, F.L., de Carvalho, M., Foguel, D., Reverter, D., Saraiva, M.J., Ventura, S.
Sci Rep
HeaderTransport Protein
Released2016-02-12
Resolution1.300
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5fw6A00 12 May, 2017 2.60.40.180 Assigned
5fw6B00 11 May, 2017 2.60.40.180 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P02766 TTHY_HUMAN Homo sapiens Transthyretin
P02766 TTHY_HUMAN Homo sapiens Transthyretin