PDB 5eam

PDB Information

PDB5EAM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-Based Optimization of a Small Molecule Antagonist of the Interaction Between WD Repeat-Containing Protein 5 (WDR5) and Mixed-Lineage Leukemia 1 (MLL1).
Getlik, M., Smil, D., Zepeda-Velazquez, C., Bolshan, Y., Poda, G., Wu, H., Dong, A., Kuznetsova, E., Marcellus, R., Senisterra, G., Dombrovski, L., Hajian, T., Kiyota, T., Schapira, M., Arrowsmith, C.H., Brown, P.J., Vedadi, M., Al-Awar, R.
J. Med. Chem.
HeaderTranscription/Transcription Inhibitor
Released2015-10-16
Resolution1.800
CATH Insert Date15 Nov, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Nov, 2015 Chopped
B 16 Nov, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5eamA00 23 Nov, 2015 2.130.10.10 Assigned
5eamB00 24 Nov, 2015 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5