PDB 5ccm

PDB Information

PDB5CCM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Mitchell, L.H., Boriack-Sjodin, P.A., Smith, S., Thomenius, M., Rioux, N., Munchhof, M., Mills, J.E., Klaus, C., Totman, J., Riera, T.V., Raimondi, A., Jacques, S.L., West, K., Foley, M., Waters, N.J., Kuntz, K.W., Wigle, T.J., Scott, M.P., Copeland, R.A., Smith, J.J., Chesworth, R.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-07-02
Resolution2.300
CATH Insert Date20 Sep, 2015

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Sep, 2015 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
5ccmA01 30 Sep, 2015 2.170.270.10 Assigned
5ccmA02 30 Sep, 2015 6.10.140.2220 Assigned
5ccmA03 30 Sep, 2015 1.10.220.160 Assigned
5ccmA04 30 Sep, 2015 1.25.40.970 Assigned
5ccmA05 30 Sep, 2015 1.25.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9H7B4 SMYD3_HUMAN Homo sapiens Histone-lysine N-methyltransferase SMYD3