PDB Information

PDB5BOT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-based discovery of indole inhibitors of matrix metalloproteinase-13.
Taylor, S.J., Abeywardane, A., Liang, S., Muegge, I., Padyana, A.K., Xiong, Z., Hill-Drzewi, M., Farmer, B., Li, X., Collins, B., Li, J.X., Heim-Riether, A., Proudfoot, J., Zhang, Q., Goldberg, D., Zuvela-Jelaska, L., Zaher, H., Li, J., Farrow, N.A.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-27
Resolution1.850
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5botA00 21 Mar, 2016 3.40.390.10 Assigned
5botB00 21 Mar, 2016 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3