PDB Information

PDB4YND
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.
Sweis, R.F., Wang, Z., Algire, M., Arrowsmith, C.H., Brown, P.J., Chiang, G.G., Guo, J., Jakob, C.G., Kennedy, S., Li, F., Maag, D., Shaw, B., Soni, N.B., Vedadi, M., Pappano, W.N.
Acs Med.Chem.Lett.
HeaderTransferase/Inhibitor
Released2015-03-09
Resolution2.790
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4yndA01 22 Jul, 2015 2.170.270.10 Assigned
4yndA02 22 Jul, 2015 Holding pen
4yndA03 22 Jul, 2015 1.25.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NRG4 SMYD2_HUMAN Homo sapiens N-lysine methyltransferase SMYD2