PDB 4xtw

PDB Links
Overview

PDB Information

PDB	4XTW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis
Primary Citation	Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. Bockman, M.R., Kalinda, A.S., Petrelli, R., De la Mora-Rey, T., Tiwari, D., Liu, F., Dawadi, S., Nandakumar, M., Rhee, K.Y., Schnappinger, D., Finzel, B.C., Aldrich, C.C. J.Med.Chem.
Header	Ligase/Ligase Inhibitor
Released	2015-01-24
Resolution	2.300
CATH Insert Date	20 Sep, 2015

PDB Images (7)

Image of CATH 4xtw

4xtw

PDB 4xtw

Image of CATH 4xtwA

4xtwA

PDB Chain 4xtwA

Image of CATH 4xtwB

4xtwB

PDB Chain 4xtwB

Image of CATH 4xtwA01

4xtwA01

CATH Domain 4xtwA01

Image of CATH 4xtwA02

4xtwA02

CATH Domain 4xtwA02

Image of CATH 4xtwB01

4xtwB01

CATH Domain 4xtwB01

Image of CATH 4xtwB02

4xtwB02

CATH Domain 4xtwB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Sep, 2015	Chopped
B	21 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xtwA01	30 Sep, 2015	3.30.930.10	Assigned
4xtwA02	30 Sep, 2015	2.30.30.100	Assigned
4xtwB01	30 Sep, 2015	3.30.930.10	Assigned
4xtwB02	30 Sep, 2015	2.30.30.100	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)