PDB 4r76

PDB Information

PDB4R76
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum fcb1/columbia
Primary Citation
Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors.
Mistry, S.N., Drinkwater, N., Ruggeri, C., Sivaraman, K.K., Loganathan, S., Fletcher, S., Drag, M., Paiardini, A., Avery, V.M., Scammells, P.J., McGowan, S.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-08-27
Resolution2.500
CATH Insert Date09 Nov, 2014

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 10 Nov, 2014 Chopped
B 10 Nov, 2014 Chopped
C 10 Nov, 2014 Chopped
D 10 Nov, 2014 Chopped
E 10 Nov, 2014 Chopped
F 10 Nov, 2014 Chopped
G 10 Nov, 2014 Chopped
H 10 Nov, 2014 Chopped
I 10 Nov, 2014 Chopped
J 10 Nov, 2014 Chopped
K 10 Nov, 2014 Chopped
L 10 Nov, 2014 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4r76A01 14 Nov, 2014 3.40.220.10 Assigned
4r76A02 14 Nov, 2014 3.40.630.10 Assigned
4r76B01 14 Nov, 2014 3.40.220.10 Assigned
4r76B02 14 Nov, 2014 3.40.630.10 Assigned
4r76C01 14 Nov, 2014 3.40.220.10 Assigned
4r76C02 14 Nov, 2014 3.40.630.10 Assigned
4r76D01 14 Nov, 2014 3.40.220.10 Assigned
4r76D02 14 Nov, 2014 3.40.630.10 Assigned
4r76E01 14 Nov, 2014 3.40.220.10 Assigned
4r76E02 14 Nov, 2014 3.40.630.10 Assigned
4r76F01 14 Nov, 2014 3.40.220.10 Assigned
4r76F02 14 Nov, 2014 3.40.630.10 Assigned
4r76G01 14 Nov, 2014 3.40.220.10 Assigned
4r76G02 14 Nov, 2014 3.40.630.10 Assigned
4r76H01 14 Nov, 2014 3.40.220.10 Assigned
4r76H02 14 Nov, 2014 3.40.630.10 Assigned
4r76I01 14 Nov, 2014 3.40.220.10 Assigned
4r76I02 14 Nov, 2014 3.40.630.10 Assigned
4r76J01 14 Nov, 2014 3.40.220.10 Assigned
4r76J02 14 Nov, 2014 3.40.630.10 Assigned
4r76K01 14 Nov, 2014 3.40.220.10 Assigned
4r76K02 14 Nov, 2014 3.40.630.10 Assigned
4r76L01 14 Nov, 2014 3.40.220.10 Assigned
4r76L02 14 Nov, 2014 3.40.630.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase