PDB Information

PDB4R5M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceVibrio cholerae O1
Primary Citation
A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Pavlovsky, A.G., Thangavelu, B., Bhansali, P., Viola, R.E.
Acta Crystallogr.,Sect.D
HeaderOxidoreductase
Released2014-08-21
Resolution1.890
CATH Insert Date21 Dec, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4r5mA01 28 Dec, 2014 3.40.50.720 Assigned
4r5mA02 28 Dec, 2014 3.30.360.10 Assigned
4r5mB01 28 Dec, 2014 3.40.50.720 Assigned
4r5mB02 28 Dec, 2014 3.30.360.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9KQG2 DHAS1_VIBCH Vibrio cholerae O1 biovar El Tor str. N16961 Aspartate-semialdehyde dehydrogenase 1
Q9KQG2 DHAS1_VIBCH Vibrio cholerae O1 biovar El Tor str. N16961 Aspartate-semialdehyde dehydrogenase 1