PDB Information

PDB4R3N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStreptococcus pneumoniae
Primary Citation
A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway.
Pavlovsky, A.G., Thangavelu, B., Bhansali, P., Viola, R.E.
Acta Crystallogr.,Sect.D
HeaderOxidoreductase
Released2014-08-16
Resolution1.350
CATH Insert Date21 Dec, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4r3nA01 28 Dec, 2014 3.40.50.720 Assigned
4r3nA02 28 Dec, 2014 3.30.360.10 Assigned
4r3nB01 28 Dec, 2014 3.40.50.720 Assigned
4r3nB02 28 Dec, 2014 3.30.360.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8DQ00 Q8DQ00_STRR6 Streptococcus pneumoniae R6 Aspartate-semialdehyde dehydrogenase
Q8DQ00 Q8DQ00_STRR6 Streptococcus pneumoniae R6 Aspartate-semialdehyde dehydrogenase
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