CATH Domain 4r3nA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.720	NAD(P)-binding Rossmann-like Domain

Domain Context

CATH Clusters

Superfamily	NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q8DQ00_STRR6

Streptococcus pneumoniae R6

Aspartate-semialdehyde dehydrogenase

PDB Structure

PDB	4R3N
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway. Pavlovsky, A.G., Thangavelu, B., Bhansali, P., Viola, R.E. Acta Crystallogr.,Sect.D