PDB 4pl4

PDB Information

PDB4PL4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors.
Sanches, M., Duffy, N.M., Talukdar, M., Thevakumaran, N., Chiovitti, D., Canny, M.D., Lee, K., Kurinov, I., Uehling, D., Al-Awar, R., Poda, G., Prakesch, M., Wilson, B., Tam, V., Schweitzer, C., Toro, A., Lucas, J.L., Vuga, D., Lehmann, L., Durocher, D., Zeng, Q., Patterson, J.B., Sicheri, F.
Nat Commun
HeaderTransferase,Hydrolase/Inhibitor
Released2014-05-16
Resolution3.000
CATH Insert Date14 Sep, 2014

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped
C 15 Sep, 2014 Chopped
D 15 Sep, 2014 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4pl4A01 16 Sep, 2014 3.30.200.20 Assigned
4pl4A02 16 Sep, 2014 1.10.510.10 Assigned
4pl4A03 16 Sep, 2014 1.20.1440.180 Assigned
4pl4B01 16 Sep, 2014 3.30.200.20 Assigned
4pl4B02 16 Sep, 2014 1.10.510.10 Assigned
4pl4B03 16 Sep, 2014 1.20.1440.180 Assigned
4pl4C01 16 Sep, 2014 3.30.200.20 Assigned
4pl4C02 16 Sep, 2014 1.10.510.10 Assigned
4pl4C03 16 Sep, 2014 1.20.1440.180 Assigned
4pl4D01 16 Sep, 2014 3.30.200.20 Assigned
4pl4D02 16 Sep, 2014 1.10.510.10 Assigned
4pl4D03 16 Sep, 2014 1.20.1440.180 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1
Q9EQY0 ERN1_MOUSE Mus musculus Serine/threonine-protein kinase/endoribonuclease IRE1