PDB 4npv

PDB Information

PDB4NPV
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1
Humphrey, J.M., Yang, E.X., Am Ende, C.W., Arnold, E.P., Head, J.L., Jenkinsonb, S., Lebel, L.A., Liras, S., Pandit, J., Samas, B., Vajdos, F., Simons, S.P., Evdokimova, A., Mansour, M., Menniti, F.S.
MEDCHEMCOMM
HeaderHydrolase/Hydrolase Inhibitor
Released2013-11-22
Resolution2.400
CATH Insert Date27 Jul, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Jul, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4npvA00 03 Aug, 2014 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q01064 PDE1B_HUMAN Homo sapiens Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B