PDB 4ms0

PDB Links
Overview

PDB Information

PDB	4MS0
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography. Recht, M.I., Sridhar, V., Badger, J., Bounaud, P.Y., Logan, C., Chie-Leon, B., Nienaber, V., Torres, F.E. J Biomol Screen
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-09-18
Resolution	1.790
CATH Insert Date	18 May, 2014

PDB Images (5)

Image of CATH 4ms0

4ms0

PDB 4ms0

Image of CATH 4ms0A

4ms0A

PDB Chain 4ms0A

Image of CATH 4ms0B

4ms0B

PDB Chain 4ms0B

Image of CATH 4ms0A00

4ms0A00

CATH Domain 4ms0A00

Image of CATH 4ms0B00

4ms0B00

CATH Domain 4ms0B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	19 May, 2014	Chopped
B	19 May, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ms0A00	21 May, 2014	1.10.1300.10	Assigned
4ms0B00	21 May, 2014	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A