PDB 4mrc

PDB Information

PDB4MRC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Mangione, P.P., Porcari, R., Gillmore, J.D., Pucci, P., Monti, M., Porcari, M., Giorgetti, S., Marchese, L., Raimondi, S., Serpell, L.C., Chen, W., Relini, A., Marcoux, J., Clatworthy, I.R., Taylor, G.W., Tennent, G.A., Robinson, C.V., Hawkins, P.N., Stoppini, M., Wood, S.P., Pepys, M.B., Bellotti, V.
Proc.Natl.Acad.Sci.USA
HeaderTransport Protein
Released2013-09-17
Resolution1.540
CATH Insert Date02 Feb, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped
B 03 Feb, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4mrcA00 07 Mar, 2014 2.60.40.180 Assigned
4mrcB00 07 Mar, 2014 2.60.40.180 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P02766 TTHY_HUMAN Homo sapiens Transthyretin
P02766 TTHY_HUMAN Homo sapiens Transthyretin