PDB 4mq1

PDB Information

PDB4MQ1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyrido[2,3-d]pyrimidines: Discovery and preliminary SAR of a novel series of DYRK1B and DYRK1A inhibitors.
Anderson, K., Chen, Y., Chen, Z., Dominique, R., Glenn, K., He, Y., Janson, C., Luk, K.C., Lukacs, C., Polonskaia, A., Qiao, Q., Railkar, A., Rossman, P., Sun, H., Xiang, Q., Vilenchik, M., Wovkulich, P., Zhang, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-09-15
Resolution2.350
CATH Insert Date15 Dec, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped
C 16 Dec, 2013 Chopped
D 16 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4mq1A01 20 Dec, 2013 3.30.200.20 Assigned
4mq1A02 20 Dec, 2013 1.10.510.10 Assigned
4mq1B01 20 Dec, 2013 3.30.200.20 Assigned
4mq1B02 20 Dec, 2013 1.10.510.10 Assigned
4mq1C01 20 Dec, 2013 3.30.200.20 Assigned
4mq1C02 20 Dec, 2013 1.10.510.10 Assigned
4mq1D01 20 Dec, 2013 3.30.200.20 Assigned
4mq1D02 20 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A