PDB 4l02

PDB Links
Overview

PDB Information

PDB	4L02
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Gustin, D.J., Li, Y., Brown, M.L., Min, X., Schmitt, M.J., Wanska, M., Wang, X., Connors, R., Johnstone, S., Cardozo, M., Cheng, A.C., Jeffries, S., Franks, B., Li, S., Shen, S., Wong, M., Wesche, H., Xu, G., Carlson, T.J., Plant, M., Morgenstern, K., Rex, K., Schmitt, J., Coxon, A., Walker, N., Kayser, F., Wang, Z. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-05-30
Resolution	2.750
CATH Insert Date	04 Aug, 2013

PDB Images (10)

Image of CATH 4l02

4l02

PDB 4l02

Image of CATH 4l02A

4l02A

PDB Chain 4l02A

Image of CATH 4l02B

4l02B

PDB Chain 4l02B

Image of CATH 4l02C

4l02C

PDB Chain 4l02C

Image of CATH 4l02A01

4l02A01

CATH Domain 4l02A01

Image of CATH 4l02A02

4l02A02

CATH Domain 4l02A02

Image of CATH 4l02B01

4l02B01

CATH Domain 4l02B01

Image of CATH 4l02B02

4l02B02

CATH Domain 4l02B02

Image of CATH 4l02C01

4l02C01

CATH Domain 4l02C01

Image of CATH 4l02C02

4l02C02

CATH Domain 4l02C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped
B	05 Aug, 2013	Chopped
C	05 Aug, 2013	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l02A01	28 Aug, 2013	3.40.50.10330	Assigned
4l02A02	28 Aug, 2013	2.60.200.40	Assigned
4l02B01	28 Aug, 2013	3.40.50.10330	Assigned
4l02B02	28 Aug, 2013	2.60.200.40	Assigned
4l02C01	28 Aug, 2013	3.40.50.10330	Assigned
4l02C02	28 Aug, 2013	2.60.200.40	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q9NYA1	SPHK1_HUMAN	Homo sapiens	Sphingosine kinase 1
Q9NYA1	SPHK1_HUMAN	Homo sapiens	Sphingosine kinase 1
Q9NYA1	SPHK1_HUMAN	Homo sapiens	Sphingosine kinase 1